Scalable Production of AAV Vectors in Orbitally Shaken HEK293 Cells
Scalable Production of AAV Vectors in Orbitally Shaken HEK293 Cells
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Publisher
United States: Elsevier Inc
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Language
English
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Publisher
United States: Elsevier Inc
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Contents
Adeno-associated virus (AAV) vectors are currently among the most commonly applied for in vivo gene therapy approaches. The evaluation of vectors during clinical development requires the production of considerable amounts of highly pure and potent vectors. Here, we set up a scalable process for AAV production, using orbitally shaken bioreactors and...
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Full title
Scalable Production of AAV Vectors in Orbitally Shaken HEK293 Cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6305802
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6305802
Other Identifiers
ISSN
2329-0501
E-ISSN
2329-0501
DOI
10.1016/j.omtm.2018.11.004