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Lactate dehydrogenase A: A key player in carcinogenesis and potential target in cancer therapy

Lactate dehydrogenase A: A key player in carcinogenesis and potential target in cancer therapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6308051

Lactate dehydrogenase A: A key player in carcinogenesis and potential target in cancer therapy

About this item

Full title

Lactate dehydrogenase A: A key player in carcinogenesis and potential target in cancer therapy

Publisher

United States: John Wiley & Sons, Inc

Journal title

Cancer medicine (Malden, MA), 2018-12, Vol.7 (12), p.6124-6136

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Elevated glycolysis remains a universal and primary character of cancer metabolism, which deeply depends on dysregulated metabolic enzymes. Lactate dehydrogenase A (LDHA) facilitates glycolytic process by converting pyruvate to lactate. Numerous researches demonstrate LDHA has an aberrantly high expression in multiple cancers, which is associated w...

Alternative Titles

Full title

Lactate dehydrogenase A: A key player in carcinogenesis and potential target in cancer therapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6308051

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6308051

Other Identifiers

ISSN

2045-7634

E-ISSN

2045-7634

DOI

10.1002/cam4.1820

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