QSAR Development for Plasma Protein Binding: Influence of the Ionization State
QSAR Development for Plasma Protein Binding: Influence of the Ionization State
About this item
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Publisher
New York: Springer US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Springer US
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Scope and Contents
Contents
ABSTRACT
Purpose
This study explored several strategies to improve the performance of literature QSAR models for plasma protein binding (PPB), such as a suitable endpoint transformation, a correct representation of chemicals, more consistency in the dataset, and a reliable definition of the applicability domain.
Methods
We retrieved hum...
Alternative Titles
Full title
QSAR Development for Plasma Protein Binding: Influence of the Ionization State
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6308215
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6308215
Other Identifiers
ISSN
0724-8741,1573-904X
E-ISSN
1573-904X
DOI
10.1007/s11095-018-2561-8
