Effects of Novel Calpain Inhibitors in Transgenic Animal Model of Parkinson’s disease/dementia with...
Effects of Novel Calpain Inhibitors in Transgenic Animal Model of Parkinson’s disease/dementia with Lewy bodies
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) are neurodegenerative disorders of the aging population characterized by the accumulation of α-synuclein (α-syn). The mechanisms triggering α-syn toxicity are not completely understood, however, c-terminus truncation of α-syn by proteases such as calpain may have a role. Therefore, inhibi...
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Effects of Novel Calpain Inhibitors in Transgenic Animal Model of Parkinson’s disease/dementia with Lewy bodies
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6308237
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6308237
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-35729-1