Single-cell RNA-seq analysis reveals the progression of human osteoarthritis
Single-cell RNA-seq analysis reveals the progression of human osteoarthritis
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Author / Creator
Ji, Quanbo , Zheng, Yuxuan , Zhang, Guoqiang , Hu, Yuqiong , Fan, Xiaoying , Hou, Yu , Wen, Lu , Li, Li , Xu, Yameng , Wang, Yan and Tang, Fuchou
Publisher
England: Elsevier Limited
Journal title
Language
English
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Publisher
England: Elsevier Limited
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Contents
ObjectivesUnderstanding the molecular mechanisms underlying human cartilage degeneration and regeneration is helpful for improving therapeutic strategies for treating osteoarthritis (OA). Here, we report the molecular programmes and lineage progression patterns controlling human OA pathogenesis using single-cell RNA sequencing (scRNA-seq).MethodsWe...
Alternative Titles
Full title
Single-cell RNA-seq analysis reveals the progression of human osteoarthritis
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6317448
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6317448
Other Identifiers
ISSN
0003-4967
E-ISSN
1468-2060
DOI
10.1136/annrheumdis-2017-212863