Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration
Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration
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Author / Creator
Ryu, Jae Kyu , Rafalski, Victoria A. , Meyer-Franke, Anke , Adams, Ryan A. , Poda, Suresh B. , Rios Coronado, Pamela E. , Pedersen, Lars Østergaard , Menon, Veena , Baeten, Kim M. , Sikorski, Shoana L. , Bedard, Catherine , Hanspers, Kristina , Bardehle, Sophia , Mendiola, Andrew S. , Davalos, Dimitrios , Machado, Michael R. , Chan, Justin P. , Plastira, Ioanna , Petersen, Mark A. , Pfaff, Samuel J. , Ang, Kenny K. , Hallenbeck, Kenneth K. , Syme, Catriona , Hakozaki, Hiroyuki , Ellisman, Mark H. , Swanson, Raymond A. , Zamvil, Scott S. , Arkin, Michelle R. , Zorn, Stevin H. , Pico, Alexander R. , Mucke, Lennart , Freedman, Stephen B. , Stavenhagen, Jeffrey B. , Nelson, Robert B. and Akassoglou, Katerina
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Activation of innate immunity and deposition of blood-derived fibrin in the central nervous system (CNS) occur in autoimmune and neurodegenerative diseases, including multiple sclerosis (MS) and Alzheimer’s disease (AD). However, the mechanisms that link disruption of the blood–brain barrier (BBB) to neurodegeneration are poorly understood, and exp...
Alternative Titles
Full title
Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration
Authors, Artists and Contributors
Author / Creator
Rafalski, Victoria A.
Meyer-Franke, Anke
Adams, Ryan A.
Poda, Suresh B.
Rios Coronado, Pamela E.
Pedersen, Lars Østergaard
Menon, Veena
Baeten, Kim M.
Sikorski, Shoana L.
Bedard, Catherine
Hanspers, Kristina
Bardehle, Sophia
Mendiola, Andrew S.
Davalos, Dimitrios
Machado, Michael R.
Chan, Justin P.
Plastira, Ioanna
Petersen, Mark A.
Pfaff, Samuel J.
Ang, Kenny K.
Hallenbeck, Kenneth K.
Syme, Catriona
Hakozaki, Hiroyuki
Ellisman, Mark H.
Swanson, Raymond A.
Zamvil, Scott S.
Arkin, Michelle R.
Zorn, Stevin H.
Pico, Alexander R.
Mucke, Lennart
Freedman, Stephen B.
Stavenhagen, Jeffrey B.
Nelson, Robert B.
Akassoglou, Katerina
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6317891
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6317891
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-018-0232-x
