Polysaccharide structure dictates mechanism of adaptive immune response to glycoconjugate vaccines
Polysaccharide structure dictates mechanism of adaptive immune response to glycoconjugate vaccines
About this item
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Glycoconjugate vaccines are among the most effective interventions for preventing several serious infectious diseases. Covalent linkage of the bacterial capsular polysaccharide to a carrier protein provides CD4⁺ T cells with epitopes that facilitate a memory response to the polysaccharide. Classically, the mechanism responsible for antigen processi...
Alternative Titles
Full title
Polysaccharide structure dictates mechanism of adaptive immune response to glycoconjugate vaccines
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6320544
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6320544
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1816401115
