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Valproic acid exerts specific cellular and molecular anti-inflammatory effects in post-operative con...

Valproic acid exerts specific cellular and molecular anti-inflammatory effects in post-operative con...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6326969

Valproic acid exerts specific cellular and molecular anti-inflammatory effects in post-operative conjunctiva

About this item

Full title

Valproic acid exerts specific cellular and molecular anti-inflammatory effects in post-operative conjunctiva

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Journal of molecular medicine (Berlin, Germany), 2019-01, Vol.97 (1), p.63-75

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Valproic acid (VPA) is a histone deacetylase inhibitor used clinically for neurological disorders. It is also potentially useful as anti-fibrotic therapy as it reduced collagen deposition in the post-operative conjunctiva. In this study, we further evaluated the effects of VPA on post-operative inflammation using the mouse model of conjunctival sca...

Alternative Titles

Full title

Valproic acid exerts specific cellular and molecular anti-inflammatory effects in post-operative conjunctiva

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6326969

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6326969

Other Identifiers

ISSN

0946-2716

E-ISSN

1432-1440

DOI

10.1007/s00109-018-1722-x

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