Exposure of Barrett’s and esophageal adenocarcinoma cells to bile acids activates EGFR–STAT3 signali...
Exposure of Barrett’s and esophageal adenocarcinoma cells to bile acids activates EGFR–STAT3 signaling axis via induction of APE1
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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The development of Barrett’s esophagus (BE) and its progression to esophageal adenocarcinoma (EAC) is highly linked to exposure to acidic bile salts due to chronic gastroesophageal reflux disease (GERD). In this study, we investigated the role of Apurinic/apyrimidinic endonuclease 1/redox effector factor-1 (APE1/REF-1) in STAT3 activation in respon...
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Full title
Exposure of Barrett’s and esophageal adenocarcinoma cells to bile acids activates EGFR–STAT3 signaling axis via induction of APE1
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6328352
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6328352
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-018-0388-8
