Minimal functional driver gene heterogeneity among untreated metastases
Minimal functional driver gene heterogeneity among untreated metastases
About this item
Full title
Author / Creator
Reiter, Johannes G. , Makohon-Moore, Alvin P. , Gerold, Jeffrey M. , Heyde, Alexander , Attiyeh, Marc A. , Kohutek, Zachary A. , Tokheim, Collin J. , Brown, Alexia , DeBlasio, Rayne M. , Niyazov, Juliana , Zucker, Amanda , Karchin, Rachel , Kinzler, Kenneth W. , Iacobuzio-Donahue, Christine A. , Vogelstein, Bert and Nowak, Martin A.
Publisher
United States: The American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: The American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Treatment decisions for cancer patients are increasingly guided by analysis of the gene mutations that drive primary tumor growth. Relatively little is known about driver gene mutations in metastases, which cause most cancer-related deaths. Reiter
et al.
explored whether the growth of different metastatic lesions within an individual patient...
Alternative Titles
Full title
Minimal functional driver gene heterogeneity among untreated metastases
Authors, Artists and Contributors
Author / Creator
Makohon-Moore, Alvin P.
Gerold, Jeffrey M.
Heyde, Alexander
Attiyeh, Marc A.
Kohutek, Zachary A.
Tokheim, Collin J.
Brown, Alexia
DeBlasio, Rayne M.
Niyazov, Juliana
Zucker, Amanda
Karchin, Rachel
Kinzler, Kenneth W.
Iacobuzio-Donahue, Christine A.
Vogelstein, Bert
Nowak, Martin A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6329287
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6329287
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aat7171
