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Buprenorphine Maintenance Subjects Are Hyperalgesic and Have No Antinociceptive Response to a Very H...

Buprenorphine Maintenance Subjects Are Hyperalgesic and Have No Antinociceptive Response to a Very H...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6329438

Buprenorphine Maintenance Subjects Are Hyperalgesic and Have No Antinociceptive Response to a Very High Morphine Dose

About this item

Full title

Buprenorphine Maintenance Subjects Are Hyperalgesic and Have No Antinociceptive Response to a Very High Morphine Dose

Publisher

England: Oxford University Press

Journal title

Pain medicine (Malden, Mass.), 2019-01, Vol.20 (1), p.119-128

Language

English

Formats

Publication information

Publisher

England: Oxford University Press

More information

Scope and Contents

Contents

Abstract
Objective
Acute pain management in opioid-dependent persons is complicated because of tolerance and opioid-induced hyperalgesia. Very high doses of morphine are ineffective in overcoming opioid-induced hyperalgesia and providing antinociception to methadone-maintained patients in an experimental setting. Whether the same occurs in bu...

Alternative Titles

Full title

Buprenorphine Maintenance Subjects Are Hyperalgesic and Have No Antinociceptive Response to a Very High Morphine Dose

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6329438

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6329438

Other Identifiers

ISSN

1526-2375

E-ISSN

1526-4637

DOI

10.1093/pm/pny025

How to access this item