Buprenorphine Maintenance Subjects Are Hyperalgesic and Have No Antinociceptive Response to a Very H...
Buprenorphine Maintenance Subjects Are Hyperalgesic and Have No Antinociceptive Response to a Very High Morphine Dose
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Publisher
England: Oxford University Press
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Language
English
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Publisher
England: Oxford University Press
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Abstract
Objective
Acute pain management in opioid-dependent persons is complicated because of tolerance and opioid-induced hyperalgesia. Very high doses of morphine are ineffective in overcoming opioid-induced hyperalgesia and providing antinociception to methadone-maintained patients in an experimental setting. Whether the same occurs in bu...
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Full title
Buprenorphine Maintenance Subjects Are Hyperalgesic and Have No Antinociceptive Response to a Very High Morphine Dose
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6329438
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6329438
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ISSN
1526-2375
E-ISSN
1526-4637
DOI
10.1093/pm/pny025