Dnase1l3 deletion causes aberrations in length and end-motif frequencies in plasma DNA
Dnase1l3 deletion causes aberrations in length and end-motif frequencies in plasma DNA
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Circulating DNA in plasma consists of short DNA fragments. The biological processes generating such fragments are not well understood. DNASE1L3 is a secreted DNASE1-like nuclease capable of digesting DNA in chromatin, and its absence causes anti-DNA responses and autoimmunity in humans and mice. We found that the deletion of Dnase1l3 in mice result...
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Full title
Dnase1l3 deletion causes aberrations in length and end-motif frequencies in plasma DNA
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6329986
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6329986
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1815031116
