Targeting lipid metabolism to overcome EMT-associated drug resistance via integrin β3/FAK pathway an...
Targeting lipid metabolism to overcome EMT-associated drug resistance via integrin β3/FAK pathway and tumor-associated macrophage repolarization using legumain-activatable delivery
About this item
Full title
Author / Creator
Jin, Hongyue , He, Yang , Zhao, Pengfei , Hu, Ying , Tao, Jin , Chen, Jiang and Huang, Yongzhuo
Publisher
Australia: Ivyspring International Publisher
Journal title
Language
English
Formats
Publication information
Publisher
Australia: Ivyspring International Publisher
Subjects
More information
Scope and Contents
Contents
Epithelial-mesenchymal transition (EMT) is closely associated with the development of drug resistance. Lipid metabolism plays an important role in EMT. This work was to study the cholesterol-lowering drug simvastatin for reversing EMT-associated resistance to chemotherapy via lipid metabolism.
The combination of simvastatin and paclitaxel was us...
Alternative Titles
Full title
Targeting lipid metabolism to overcome EMT-associated drug resistance via integrin β3/FAK pathway and tumor-associated macrophage repolarization using legumain-activatable delivery
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6332796
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6332796
Other Identifiers
ISSN
1838-7640
E-ISSN
1838-7640
DOI
10.7150/thno.27246
