Dopamine D2 receptor occupancy of lumateperone (ITI-007): a Positron Emission Tomography Study in pa...
Dopamine D2 receptor occupancy of lumateperone (ITI-007): a Positron Emission Tomography Study in patients with schizophrenia
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New York: Nature Publishing Group
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English
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New York: Nature Publishing Group
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Dopamine D2 receptor occupancy (D2RO) is a key feature of all currently approved antipsychotic medications. However, antipsychotic efficacy associated with high D2RO is often limited by side effects such as motor disturbances and hyperprolactinemia. Lumateperone (ITI-007) is a first-in-class selective and simultaneous modulator of serotonin, dopami...
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Dopamine D2 receptor occupancy of lumateperone (ITI-007): a Positron Emission Tomography Study in patients with schizophrenia
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6333832
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6333832
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ISSN
0893-133X
E-ISSN
1740-634X
DOI
10.1038/s41386-018-0251-1
