TIP60-dependent acetylation of the SPZ1-TWIST complex promotes epithelial–mesenchymal transition and...
TIP60-dependent acetylation of the SPZ1-TWIST complex promotes epithelial–mesenchymal transition and metastasis in liver cancer
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Metastasis is the main cause of cancer mortality. However, the triggering mechanisms and regulation of epithelial–mesenchymal transition (EMT) factors in the commitment of metastasis have not been well characterized. Spermatogenic Zip 1 (SPZ1) acts as a proto-oncogene and an upstream regulator of EMT during tumorigenesis. Here we report that the HI...
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TIP60-dependent acetylation of the SPZ1-TWIST complex promotes epithelial–mesenchymal transition and metastasis in liver cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6345675
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6345675
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-018-0457-z