Toll-like Receptor 3 Is a Therapeutic Target for Pulmonary Hypertension
Toll-like Receptor 3 Is a Therapeutic Target for Pulmonary Hypertension
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Author / Creator
Farkas, Daniela , Thompson, A A Roger , Bhagwani, Aneel R , Hultman, Schuyler , Ji, Hyun , Kotha, Naveen , Farr, Grant , Arnold, Nadine D , Braithwaite, Adam , Casbolt, Helen , Cole, Jennifer E , Sabroe, Ian , Monaco, Claudia , Cool, Carlyne D , Goncharova, Elena A , Lawrie, Allan and Farkas, Laszlo
Publisher
United States: American Thoracic Society
Journal title
Language
English
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Publication information
Publisher
United States: American Thoracic Society
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Scope and Contents
Contents
Pulmonary arterial hypertension (PAH) is characterized by vascular cell proliferation and endothelial cell apoptosis. TLR3 (Toll-like receptor 3) is a receptor for double-stranded RNA and has been recently implicated in vascular protection.
To study the expression and role of TLR3 in PAH and to determine whether a TLR3 agonist reduces pulmonary...
Alternative Titles
Full title
Toll-like Receptor 3 Is a Therapeutic Target for Pulmonary Hypertension
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6353001
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6353001
Other Identifiers
ISSN
1073-449X
E-ISSN
1535-4970
DOI
10.1164/rccm.201707-1370OC
