Log in to save to my catalogue

APC-activated long noncoding RNA inhibits colorectal carcinoma pathogenesis through reduction of exo...

APC-activated long noncoding RNA inhibits colorectal carcinoma pathogenesis through reduction of exo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6355227

APC-activated long noncoding RNA inhibits colorectal carcinoma pathogenesis through reduction of exosome production

About this item

Full title

APC-activated long noncoding RNA inhibits colorectal carcinoma pathogenesis through reduction of exosome production

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2019-02, Vol.129 (2), p.727-743

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

The adenomatous polyposis coli (APC) gene plays a pivotal role in the pathogenesis of colorectal carcinoma (CRC) but remains a challenge for drug development. Long noncoding RNAs (lncRNAs) are invaluable in identifying cancer pathologies and providing therapeutic options for patients with cancer. Here, we identified a lncRNA (lncRNA-APC1) activated...

Alternative Titles

Full title

APC-activated long noncoding RNA inhibits colorectal carcinoma pathogenesis through reduction of exosome production

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6355227

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6355227

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI122478

How to access this item