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Misactivation of Hedgehog signaling causes inherited and sporadic cancers

Misactivation of Hedgehog signaling causes inherited and sporadic cancers

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6355229

Misactivation of Hedgehog signaling causes inherited and sporadic cancers

About this item

Full title

Misactivation of Hedgehog signaling causes inherited and sporadic cancers

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2019-02, Vol.129 (2), p.465-475

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

The Hedgehog pathway is critical for the development of diverse organs. Misactivation of the Hedgehog pathway can cause developmental abnormalities and cancers, including medulloblastoma, the most common pediatric brain tumor, and basal cell carcinoma, the most common cancer in the United States. Here, we review how basic, translational, and clinic...

Alternative Titles

Full title

Misactivation of Hedgehog signaling causes inherited and sporadic cancers

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6355229

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6355229

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI120850

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