Methylglyoxal down-regulates the expression of cell cycle associated genes and activates the p53 pat...
Methylglyoxal down-regulates the expression of cell cycle associated genes and activates the p53 pathway in human umbilical vein endothelial cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Although methylglyoxal (MGO) has emerged as key mediator of diabetic microvascular complications, the influence of MGO on the vascular transcriptome has not thoroughly been assessed. Since diabetes is associated with low grade inflammation causing sustained nuclear factor-kappa B (NF-κB) activation, the current study addressed 1) to what extent MGO...
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Methylglyoxal down-regulates the expression of cell cycle associated genes and activates the p53 pathway in human umbilical vein endothelial cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6362029
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6362029
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-37937-1
