Extensive sex differences at the initiation of genetic recombination
Extensive sex differences at the initiation of genetic recombination
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Meiotic recombination differs between males and females; however, when and how these differences are established is unknown. Here we identify extensive sex differences at the initiation of recombination by mapping hotspots of meiotic DNA double-strand breaks in male and female mice. Contrary to past findings in humans, few hotspots are used uniquel...
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Full title
Extensive sex differences at the initiation of genetic recombination
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6364566
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6364566
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-018-0492-5
