Cytotoxic CD8⁺ T lymphocytes expressing ALS-causing SOD1 mutant selectively trigger death of spinal...
Cytotoxic CD8⁺ T lymphocytes expressing ALS-causing SOD1 mutant selectively trigger death of spinal motoneurons
About this item
Full title
Author / Creator
Coque, Emmanuelle , Salsac, Céline , Espinosa-Carrasco, Gabriel , Varga, Béla , Degauque, Nicolas , Cadoux, Marion , Crabé, Roxane , Virenque, Anaïs , Soulard, Claire , Fierle, Julie K. , Brodovitch, Alexandre , Libralato, Margot , Végh, Attila G. , Venteo, Stéphanie , Scamps, Frédérique , Boucraut, José , Laplaud, David , Hernandez, Javier , Gergely, Csilla , Vincent, Thierry and Raoul, Cédric
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Adaptive immune response is part of the dynamic changes that accompany motoneuron loss in amyotrophic lateral sclerosis (ALS). CD4+ T cells that regulate a protective immunity during the neurodegenerative process have received the most attention. CD8⁺ T cells are also observed in the spinal cord of patients and ALS mice although their contribution...
Alternative Titles
Full title
Cytotoxic CD8⁺ T lymphocytes expressing ALS-causing SOD1 mutant selectively trigger death of spinal motoneurons
Authors, Artists and Contributors
Author / Creator
Salsac, Céline
Espinosa-Carrasco, Gabriel
Varga, Béla
Degauque, Nicolas
Cadoux, Marion
Crabé, Roxane
Virenque, Anaïs
Soulard, Claire
Fierle, Julie K.
Brodovitch, Alexandre
Libralato, Margot
Végh, Attila G.
Venteo, Stéphanie
Scamps, Frédérique
Boucraut, José
Laplaud, David
Hernandez, Javier
Gergely, Csilla
Vincent, Thierry
Raoul, Cédric
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6369778
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6369778
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1815961116
