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T cell receptor cross-reactivity expanded by dramatic peptide–MHC adaptability

T cell receptor cross-reactivity expanded by dramatic peptide–MHC adaptability

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6371774

T cell receptor cross-reactivity expanded by dramatic peptide–MHC adaptability

About this item

Full title

T cell receptor cross-reactivity expanded by dramatic peptide–MHC adaptability

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2018-10, Vol.14 (10), p.934-942

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

T cell receptor cross-reactivity allows a fixed T cell repertoire to respond to a much larger universe of potential antigens. Recent work has emphasized the importance of peptide structural and chemical homology, as opposed to sequence similarity, in T cell receptor cross-reactivity. Surprisingly, though, T cell receptors can also cross-react betwe...

Alternative Titles

Full title

T cell receptor cross-reactivity expanded by dramatic peptide–MHC adaptability

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6371774

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6371774

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/s41589-018-0130-4

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