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Fasciola hepatica GST downregulates NF-κB pathway effectors and inflammatory cytokines while promoti...

Fasciola hepatica GST downregulates NF-κB pathway effectors and inflammatory cytokines while promoti...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6381083

Fasciola hepatica GST downregulates NF-κB pathway effectors and inflammatory cytokines while promoting survival in a mouse septic shock model

About this item

Full title

Fasciola hepatica GST downregulates NF-κB pathway effectors and inflammatory cytokines while promoting survival in a mouse septic shock model

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2019-02, Vol.9 (1), p.2275, Article 2275

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Parasitic helminths and helminth-derived molecules have demonstrated to possess powerful anti-inflammatory properties and confirmed therapeutic effects on inflammatory diseases. The helminth
Fasciola hepatica
has been reported to suppress specific Th1 specific immune responses induced by concurrent bacterial infections, thus demonstrating its...

Alternative Titles

Full title

Fasciola hepatica GST downregulates NF-κB pathway effectors and inflammatory cytokines while promoting survival in a mouse septic shock model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6381083

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6381083

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-018-37652-x

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