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Morphing of Ibogaine: A Successful Attempt into the Search for Sigma-2 Receptor Ligands

Morphing of Ibogaine: A Successful Attempt into the Search for Sigma-2 Receptor Ligands

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6386901

Morphing of Ibogaine: A Successful Attempt into the Search for Sigma-2 Receptor Ligands

About this item

Full title

Morphing of Ibogaine: A Successful Attempt into the Search for Sigma-2 Receptor Ligands

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2019-01, Vol.20 (3), p.488

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Ibogaine is a psychoactive indole alkaloid with high affinity for several targets including the σ2 receptor. Indeed, extensive data support the involvement of the σ2 receptor in neurological disorders, including Alzheimer’s disease, schizophrenia, alcohol abuse and pain. Due to its serious side effects which prevent ibogaine from potential clinical...

Alternative Titles

Full title

Morphing of Ibogaine: A Successful Attempt into the Search for Sigma-2 Receptor Ligands

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6386901

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6386901

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms20030488

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