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Acute silencing of hippocampal CA3 reveals a dominant role in place field responses

Acute silencing of hippocampal CA3 reveals a dominant role in place field responses

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6387637

Acute silencing of hippocampal CA3 reveals a dominant role in place field responses

About this item

Full title

Acute silencing of hippocampal CA3 reveals a dominant role in place field responses

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2019-03, Vol.22 (3), p.337-342

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Neurons in hippocampal output area CA1 are thought to exhibit redundancy across cortical and hippocampal inputs. Here we show instead that acute silencing of CA3 terminals drastically reduces place field responses for many CA1 neurons, while a smaller number are unaffected or have increased responses. These results imply that CA3 is the predominant...

Alternative Titles

Full title

Acute silencing of hippocampal CA3 reveals a dominant role in place field responses

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6387637

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6387637

Other Identifiers

ISSN

1097-6256

E-ISSN

1546-1726

DOI

10.1038/s41593-018-0321-z

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