Podocyte histone deacetylase activity regulates murine and human glomerular diseases
Podocyte histone deacetylase activity regulates murine and human glomerular diseases
About this item
Full title
Author / Creator
Inoue, Kazunori , Gan, Geliang , Ciarleglio, Maria , Zhang, Yan , Tian, Xuefei , Pedigo, Christopher E. , Cavanaugh, Corey , Tate, Janet , Wang, Ying , Cross, Elizabeth , Groener, Marwin , Chai, Nathan , Wang, Zhen , Justice, Amy , Zhang, Zhenhai , Parikh, Chirag R. , Wilson, Francis P. and Ishibe, Shuta
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publication information
Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
We identified 2 genes, histone deacetylase 1 (HDAC1) and HDAC2, contributing to the pathogenesis of proteinuric kidney diseases, the leading cause of end-stage kidney disease. mRNA expression profiling from proteinuric mouse glomeruli was linked to Connectivity Map databases, identifying HDAC1 and HDAC2 with the differentially expressed gene set re...
Alternative Titles
Full title
Podocyte histone deacetylase activity regulates murine and human glomerular diseases
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6391095
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6391095
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI124030
