Mesalamine and azathioprine modulate junctional complexes and restore epithelial barrier function in...
Mesalamine and azathioprine modulate junctional complexes and restore epithelial barrier function in intestinal inflammation
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Disruption of mucosal structure and barrier function contribute to the pathogenesis of inflammatory bowel disease (IBD). Efficacy of therapy in IBD is based on endoscopic mucosal healing, which occurs by a dynamic interplay of epithelial cell regeneration, migration and differentiation. Both mesalamine (5-ASA) and azathioprine (AZTP) promote this p...
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Full title
Mesalamine and azathioprine modulate junctional complexes and restore epithelial barrier function in intestinal inflammation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6391397
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6391397
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-39401-0
