Palladium based nanoparticles for the treatment of advanced melanoma
Palladium based nanoparticles for the treatment of advanced melanoma
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
IGF1R and CD44 are overexpressed in most advanced melanomas so we designed chemotherapeutic nanoparticles to target those receptors. Tris(dibenzylideneacetone)dipalladium (Tris DBA-Pd) is a novel inhibitor of
N
-myristoyltransferase 1 (NMT-1) and has proven
in vivo
activity against melanoma. However, poor solubility impairs its effectiv...
Alternative Titles
Full title
Palladium based nanoparticles for the treatment of advanced melanoma
Authors, Artists and Contributors
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6397149
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6397149
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-40258-6
