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Infiltration of CD8⁺ T cells into tumor cell clusters in triple-negative breast cancer

Infiltration of CD8⁺ T cells into tumor cell clusters in triple-negative breast cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6397588

Infiltration of CD8⁺ T cells into tumor cell clusters in triple-negative breast cancer

About this item

Full title

Infiltration of CD8⁺ T cells into tumor cell clusters in triple-negative breast cancer

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2019-02, Vol.116 (9), p.3678-3687

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Infiltration of CD8⁺ T lymphocytes into solid tumors is associated with good prognosis in various types of cancer, including triple-negative breast cancer (TNBC). However, the mechanisms underlying different infiltration levels are largely unknown. Here, we have characterized the spatial profile of CD8⁺ T cells around tumor cell clusters (tightly c...

Alternative Titles

Full title

Infiltration of CD8⁺ T cells into tumor cell clusters in triple-negative breast cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6397588

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6397588

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1817652116

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