Neuronal AMP-activated protein kinase hyper-activation induces synaptic loss by an autophagy-mediate...
Neuronal AMP-activated protein kinase hyper-activation induces synaptic loss by an autophagy-mediated process
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by synaptic loss that leads to the development of cognitive deficits. Synapses are neuronal structures that play a crucial role in memory formation and are known to consume most of the energy used in the brain. Interestingly, AMP-activated protein kinase (AMPK), the main intrace...
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Full title
Neuronal AMP-activated protein kinase hyper-activation induces synaptic loss by an autophagy-mediated process
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6399353
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6399353
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-019-1464-x
