Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biob...
Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank
About this item
Full title
Author / Creator
Tachmazidou, Ioanna , Hatzikotoulas, Konstantinos , Southam, Lorraine , Esparza-Gordillo, Jorge , Haberland, Valeriia , Zheng, Jie , Johnson, Toby , Koprulu, Mine , Zengini, Eleni , Steinberg, Julia , Wilkinson, Jeremy M , Bhatnagar, Sahir , Hoffman, Joshua D , Buchan, Natalie , Süveges, Dániel , Yerges-Armstrong, Laura , Smith, George Davey , Gaunt, Tom R , Scott, Robert A , McCarthy, Linda C and Zeggini, Eleftheria
Journal title
Language
English
Formats
More information
Scope and Contents
Contents
Osteoarthritis is the most common musculoskeletal disease and the leading cause of disability globally. Here, we perform a genome-wide association study for osteoarthritis (77,052 cases and 378,169 controls), analysing 4 phenotypes: knee osteoarthritis, hip osteoarthritis, knee and/or hip osteoarthritis, and any osteoarthritis. We discover 64 signa...
Alternative Titles
Full title
Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank
Authors, Artists and Contributors
Author / Creator
Hatzikotoulas, Konstantinos
Southam, Lorraine
Esparza-Gordillo, Jorge
Haberland, Valeriia
Zheng, Jie
Johnson, Toby
Koprulu, Mine
Zengini, Eleni
Steinberg, Julia
Wilkinson, Jeremy M
Bhatnagar, Sahir
Hoffman, Joshua D
Buchan, Natalie
Süveges, Dániel
Yerges-Armstrong, Laura
Smith, George Davey
Gaunt, Tom R
Scott, Robert A
McCarthy, Linda C
Zeggini, Eleftheria
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6400267
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6400267
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/s41588-018-0327-1
