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PLD-dependent phosphatidic acid microdomains are signaling platforms for podosome formation

PLD-dependent phosphatidic acid microdomains are signaling platforms for podosome formation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6401089

PLD-dependent phosphatidic acid microdomains are signaling platforms for podosome formation

About this item

Full title

PLD-dependent phosphatidic acid microdomains are signaling platforms for podosome formation

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2019-03, Vol.9 (1), p.3556-3556, Article 3556

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Local membrane phospholipid enrichment serves as docking platform for signaling proteins involved in many processes including cell adhesion and migration. Tissue-resident dendritic cells (DCs) assemble actomyosin-based structures called podosomes, which mediate adhesion and degradation of extracellular matrix for migration and antigen sampling. Rec...

Alternative Titles

Full title

PLD-dependent phosphatidic acid microdomains are signaling platforms for podosome formation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6401089

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6401089

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-019-39358-0

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