Activated platelets in the tumor microenvironment for targeting of antibody-drug conjugates to tumor...
Activated platelets in the tumor microenvironment for targeting of antibody-drug conjugates to tumors and metastases
About this item
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Author / Creator
Publisher
Australia: Ivyspring International Publisher
Journal title
Language
English
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Publication information
Publisher
Australia: Ivyspring International Publisher
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Scope and Contents
Contents
: Platelets are increasingly recognized as mediators of tumor growth and metastasis. Hypothesizing that activated platelets in the tumor microenvironment provide a targeting epitope for tumor-directed chemotherapy, we developed an antibody-drug conjugate (ADC), comprised of a single-chain antibody (scFv) against the platelet integrin GPIIb/IIIa (sc...
Alternative Titles
Full title
Activated platelets in the tumor microenvironment for targeting of antibody-drug conjugates to tumors and metastases
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6401411
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6401411
Other Identifiers
ISSN
1838-7640
E-ISSN
1838-7640
DOI
10.7150/thno.29146
