Methodological refinement of Aldara-induced psoriasiform dermatitis model in mice
Methodological refinement of Aldara-induced psoriasiform dermatitis model in mice
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Imiquimod (IMQ)-induced skin inflammation is currently the most widely accepted psoriasis animal model, however, it features several limitations. We have modified the IMQ-model to minimize its systemic effects towards effectively maintaining the characteristic skin reactions. The original protocol (OP) uses 62.5 mg Aldara cream (or vaseline) on the...
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Methodological refinement of Aldara-induced psoriasiform dermatitis model in mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6403245
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6403245
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-39903-x
