Hybrid approach to sieve out natural compounds against dual targets in Alzheimer’s Disease
Hybrid approach to sieve out natural compounds against dual targets in Alzheimer’s Disease
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Excess Aβ production by the key protease BACE1, results in Aβ aggregation, forming amyloid plaques, all of which contribute to the pathogenesis of Alzheimer
’
s disease. Besides the multi-factorial nature of the disease, the diversity in the size and shape of known ligands that bind to the active site of BACE1, that is the flexibility of the...
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Full title
Hybrid approach to sieve out natural compounds against dual targets in Alzheimer’s Disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6403309
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6403309
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-40271-9
