Structural and Functional Biology of Aldo-Keto Reductase Steroid-Transforming Enzymes
Structural and Functional Biology of Aldo-Keto Reductase Steroid-Transforming Enzymes
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Washington, DC: Endocrine Society
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Language
English
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Washington, DC: Endocrine Society
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Abstract
Aldo-keto reductases (AKRs) are monomeric NAD(P)(H)-dependent oxidoreductases that play pivotal roles in the biosynthesis and metabolism of steroids in humans. AKR1C enzymes acting as 3-ketosteroid, 17-ketosteroid, and 20-ketosteroid reductases are involved in the prereceptor regulation of ligands for the androgen, estrogen, and progest...
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Full title
Structural and Functional Biology of Aldo-Keto Reductase Steroid-Transforming Enzymes
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6405412
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6405412
Other Identifiers
ISSN
0163-769X
E-ISSN
1945-7189
DOI
10.1210/er.2018-00089
