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RNA Stabilizes Transcription-Dependent Chromatin Loops Induced By Nuclear Hormones

RNA Stabilizes Transcription-Dependent Chromatin Loops Induced By Nuclear Hormones

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6408484

RNA Stabilizes Transcription-Dependent Chromatin Loops Induced By Nuclear Hormones

About this item

Full title

RNA Stabilizes Transcription-Dependent Chromatin Loops Induced By Nuclear Hormones

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2019-03, Vol.9 (1), p.3925-3925, Article 3925

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

We show that transcription induced by nuclear receptors for estrogen (E
2
) or retinoic acid (RA) is associated with formation of chromatin loops that juxtapose the 5’ end (containing the promoter) with the enhancer and the 3′ polyA addition site of the target gene. We find three loop configurations which change as a function of time after in...

Alternative Titles

Full title

RNA Stabilizes Transcription-Dependent Chromatin Loops Induced By Nuclear Hormones

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6408484

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6408484

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-019-40123-6

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