RNA Stabilizes Transcription-Dependent Chromatin Loops Induced By Nuclear Hormones
RNA Stabilizes Transcription-Dependent Chromatin Loops Induced By Nuclear Hormones
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
We show that transcription induced by nuclear receptors for estrogen (E
2
) or retinoic acid (RA) is associated with formation of chromatin loops that juxtapose the 5’ end (containing the promoter) with the enhancer and the 3′ polyA addition site of the target gene. We find three loop configurations which change as a function of time after in...
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RNA Stabilizes Transcription-Dependent Chromatin Loops Induced By Nuclear Hormones
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6408484
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6408484
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-40123-6