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Berberine prevents human nucleus pulposus cells from IL‑1β‑induced extracellular matrix degradation...

Berberine prevents human nucleus pulposus cells from IL‑1β‑induced extracellular matrix degradation...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6414164

Berberine prevents human nucleus pulposus cells from IL‑1β‑induced extracellular matrix degradation and apoptosis by inhibiting the NF‑κB pathway

About this item

Full title

Berberine prevents human nucleus pulposus cells from IL‑1β‑induced extracellular matrix degradation and apoptosis by inhibiting the NF‑κB pathway

Publisher

Athens: Spandidos Publications UK Ltd

Journal title

International journal of molecular medicine, 2019-04, Vol.43 (4), p.1679-1686

Language

English

Formats

Publication information

Publisher

Athens: Spandidos Publications UK Ltd

More information

Scope and Contents

Contents

Intervertebral disc degeneration (IDD) is widely considered to be one of the main causes of lower back pain, which is a chronic progressive disease closely related to inflammation, nucleus pulposus (NP) cell apoptosis and extracellular matrix (ECM) degradation. Berberine (BBR) is an alkaloid compound with an anti-inflammatory effect and has been re...

Alternative Titles

Full title

Berberine prevents human nucleus pulposus cells from IL‑1β‑induced extracellular matrix degradation and apoptosis by inhibiting the NF‑κB pathway

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6414164

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6414164

Other Identifiers

ISSN

1107-3756

E-ISSN

1791-244X

DOI

10.3892/ijmm.2019.4105

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