The immunosuppressant drug azathioprine restrains adipogenesis of muscle Fibro/Adipogenic Progenitor...
The immunosuppressant drug azathioprine restrains adipogenesis of muscle Fibro/Adipogenic Progenitors from dystrophic mice by affecting AKT signaling
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Fibro/Adipogenic Progenitors (FAPs) define a stem cell population playing a pro-regenerative role after muscle damage. When removed from their natural niche, FAPs readily differentiate into adipocytes or fibroblasts. This digressive differentiation potential, which is kept under tight control in the healthy muscle niche, contributes to fat and scar...
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The immunosuppressant drug azathioprine restrains adipogenesis of muscle Fibro/Adipogenic Progenitors from dystrophic mice by affecting AKT signaling
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6416262
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6416262
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-39538-y
