Disruption of CUL3-mediated ubiquitination causes proximal tubule injury and kidney fibrosis
Disruption of CUL3-mediated ubiquitination causes proximal tubule injury and kidney fibrosis
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Cullin 3 (CUL3) is part of the ubiquitin proteasomal system and controls several cellular processes critical for normal organ function including the cell cycle, and Keap1/Nrf2 signaling. Kidney tubule-specific
Cul3
disruption causes tubulointerstitial fibrosis, but little is known about the mechanisms. Therefore, we tested the hypothesis that...
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Full title
Disruption of CUL3-mediated ubiquitination causes proximal tubule injury and kidney fibrosis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6418206
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6418206
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-40795-0
