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Dichloroacetic acid upregulates apoptosis of ovarian cancer cells by regulating mitochondrial functi...

Dichloroacetic acid upregulates apoptosis of ovarian cancer cells by regulating mitochondrial functi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6419601

Dichloroacetic acid upregulates apoptosis of ovarian cancer cells by regulating mitochondrial function

About this item

Full title

Dichloroacetic acid upregulates apoptosis of ovarian cancer cells by regulating mitochondrial function

Publisher

New Zealand: Taylor & Francis Ltd

Journal title

OncoTargets and therapy, 2019-01, Vol.12, p.1729-1739

Language

English

Formats

Publication information

Publisher

New Zealand: Taylor & Francis Ltd

More information

Scope and Contents

Contents

Metabolic reprogramming is a characteristic of tumor cells and is considered a potential therapeutic target. Even under aerobic conditions, tumor cells use glycolysis to produce energy, a phenomenon called the "Warburg effect". Pyruvate dehydrogenase kinase 1 (PDK1) is a key factor linking glycolysis and the tricarboxylic acid cycle. Dichloroacetic...

Alternative Titles

Full title

Dichloroacetic acid upregulates apoptosis of ovarian cancer cells by regulating mitochondrial function

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6419601

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6419601

Other Identifiers

ISSN

1178-6930

E-ISSN

1178-6930

DOI

10.2147/OTT.S194329

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