A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and ma...
A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis
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Author / Creator
Morgan, Marcos , Kabayama, Yuka , Much, Christian , Ivanova, Ivayla , Di Giacomo, Monica , Auchynnikava, Tatsiana , Monahan, Jack Michael , Vitsios, Dimitrios Michael , Vasiliauskaitė, Lina , Comazzetto, Stefano , Rappsilber, Juri , Allshire, Robin Campbell , Porse, Bo Torben , Enright, Anton James and O’Carroll, Dónal
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Several developmental stages of spermatogenesis are transcriptionally quiescent which presents major challenges associated with the regulation of gene expression. Here we identify that the zygotene to pachytene transition is not only associated with the resumption of transcription but also a wave of programmed mRNA degradation that is essential for...
Alternative Titles
Full title
A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis
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Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6420129
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6420129
Other Identifiers
ISSN
1001-0602
E-ISSN
1748-7838
DOI
10.1038/s41422-018-0128-1
