DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation
DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Failure of the heat shock response is a key event that leads to insulin resistance and type 2 diabetes. We recently showed that DNAJB3 co-chaperone is downregulated in obese and diabetic patients and that physical exercise restores its normal expression with a significant improvement of the clinical outcomes. In 3T3-L1 adipocytes, DNAJB3 has a role...
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DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6423224
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6423224
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-41244-8