A secreted PD-L1 splice variant that covalently dimerizes and mediates immunosuppression
A secreted PD-L1 splice variant that covalently dimerizes and mediates immunosuppression
About this item
Full title
Author / Creator
Mahoney, Kathleen M. , Shukla, Sachet A. , Patsoukis, Nikolaos , Chaudhri, Apoorvi , Browne, Edward P. , Arazi, Arnon , Eisenhaure, Thomas M. , Pendergraft, William F. , Hua, Ping , Pham, Hung C. , Bu, Xia , Zhu, Baogong , Hacohen, Nir , Fritsch, Edward F. , Boussiotis, Vassiliki A. , Wu, Catherine J. and Freeman, Gordon J.
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Targeting immune checkpoint pathways, such as programmed death ligand-1 (PD-L1, also known as CD274 or B7-H1) or its receptor programmed cell death-1 (PD-1) has shown improved survival for patients with numerous types of cancers, not limited to lung cancer, melanoma, renal cell carcinoma, and Hodgkin lymphoma. PD-L1 is a co-inhibitory molecule whos...
Alternative Titles
Full title
A secreted PD-L1 splice variant that covalently dimerizes and mediates immunosuppression
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6426808
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6426808
Other Identifiers
ISSN
0340-7004
E-ISSN
1432-0851
DOI
10.1007/s00262-018-2282-1
