Phenylpyrrole fungicides act on triosephosphate isomerase to induce methylglyoxal stress and alter h...
Phenylpyrrole fungicides act on triosephosphate isomerase to induce methylglyoxal stress and alter hybrid histidine kinase activity
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Fludioxonil, a natural product of pyrrolnitrin, is a potent fungicide used on crops worldwide. Drug action requires the presence of a group III hybrid histidine kinase (HHK) and the
h
igh
o
smolarity
g
lycerol (HOG) pathway. We have reported that the drug does not act directly on HHK, but triggers the conversion of the kinase to a...
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Full title
Phenylpyrrole fungicides act on triosephosphate isomerase to induce methylglyoxal stress and alter hybrid histidine kinase activity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6433957
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6433957
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-41564-9