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Effects of elamipretide on skeletal muscle in dogs with experimentally induced heart failure

Effects of elamipretide on skeletal muscle in dogs with experimentally induced heart failure

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6437430

Effects of elamipretide on skeletal muscle in dogs with experimentally induced heart failure

About this item

Full title

Effects of elamipretide on skeletal muscle in dogs with experimentally induced heart failure

Publisher

England: John Wiley & Sons, Inc

Journal title

ESC Heart Failure, 2019-04, Vol.6 (2), p.328-335

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Aims
Elamipretide (ELAM), an aromatic–cationic tetrapeptide, interacts with cardiolipin and normalizes dysfunctional mitochondria of cardiomyocytes. This study examined the effects of ELAM on skeletal muscle mitochondria function in dogs with chronic heart failure (HF).
Methods and results
Studies were performed in skeletal muscle biopsy s...

Alternative Titles

Full title

Effects of elamipretide on skeletal muscle in dogs with experimentally induced heart failure

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6437430

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6437430

Other Identifiers

ISSN

2055-5822

E-ISSN

2055-5822

DOI

10.1002/ehf2.12408

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