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Vinculin Force Sensor Detects Tumor-Osteocyte Interactions

Vinculin Force Sensor Detects Tumor-Osteocyte Interactions

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6449341

Vinculin Force Sensor Detects Tumor-Osteocyte Interactions

About this item

Full title

Vinculin Force Sensor Detects Tumor-Osteocyte Interactions

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2019-04, Vol.9 (1), p.5615-5615, Article 5615

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

This study utilized a Förster resonance energy transfer (FRET)-based molecular tension sensor and live cell imaging to evaluate the effect of osteocytes, a mechanosensitive bone cell, on the migratory behavior of tumor cells. Two cell lines derived from MDA-MB-231 breast cancer cells were transfected with the vinculin tension sensor to quantitative...

Alternative Titles

Full title

Vinculin Force Sensor Detects Tumor-Osteocyte Interactions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6449341

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6449341

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-019-42132-x

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