Podocyte-specific Nox4 deletion affords renoprotection in a mouse model of diabetic nephropathy
Podocyte-specific Nox4 deletion affords renoprotection in a mouse model of diabetic nephropathy
About this item
Full title
Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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More information
Scope and Contents
Contents
Aims/hypothesis
Changes in podocyte morphology and function are associated with albuminuria and progression of diabetic nephropathy. NADPH oxidase 4 (NOX4) is the main source of reactive oxygen species (ROS) in the kidney and
Nox4
is upregulated in podocytes in response to high glucose. We assessed the role of NOX4-derived ROS in podocytes...
Alternative Titles
Full title
Podocyte-specific Nox4 deletion affords renoprotection in a mouse model of diabetic nephropathy
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6450410
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6450410
Other Identifiers
ISSN
0012-186X
E-ISSN
1432-0428
DOI
10.1007/s00125-015-3796-0
