Neuroinflammation induced by lipopolysaccharide causes cognitive impairment in mice
Neuroinflammation induced by lipopolysaccharide causes cognitive impairment in mice
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Author / Creator
Zhao, Jiayi , Bi, Wei , Xiao, Shu , Lan, Xin , Cheng, Xiaofeng , Zhang, Jiawei , Lu, Daxiang , Wei, Wei , Wang, Yanping , Li, Hongmei , Fu, Yongmei and Zhu, Lihong
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
In this study, we investigated lipopolysaccharide (LPS)-induced cognitive impairment and neuroinflammation in C57BL/6J mice by using behavioral tests, immunofluorescence, enzyme-linked immunosorbent assay (ELISA) and Western blot. We found that LPS treatment leads to sickness behavior and cognitive impairment in mice as shown in the Morris water ma...
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Full title
Neuroinflammation induced by lipopolysaccharide causes cognitive impairment in mice
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6453933
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6453933
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-42286-8
