Pioglitazone Therapy of PAX8-PPARγ Fusion Protein Thyroid Carcinoma
Pioglitazone Therapy of PAX8-PPARγ Fusion Protein Thyroid Carcinoma
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Publisher
Washington, DC: Endocrine Society
Journal title
Language
English
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Publisher
Washington, DC: Endocrine Society
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Abstract
Context
A subset of thyroid carcinomas expresses an oncogenic paired box 8 (PAX8) and peroxisome proliferator activated receptor γ (PPARγ) fusion protein (PPFP). The PPARγ/PPFP ligand pioglitazone is highly therapeutic in a transgenic mouse model of PPFP thyroid carcinoma, but whether pioglitazone is therapeutic in patients with PPFP...
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Full title
Pioglitazone Therapy of PAX8-PPARγ Fusion Protein Thyroid Carcinoma
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6456920
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6456920
Other Identifiers
ISSN
0021-972X
E-ISSN
1945-7197
DOI
10.1210/jc.2017-02533
